Lipoproteins Are Critical TLR2 Activating Toxins in Group B Streptococcal Sepsis
نویسندگان
چکیده
منابع مشابه
Lipoproteins are critical TLR2 activating toxins in group B streptococcal sepsis.
Group B streptococcus (GBS) is the most important cause of neonatal sepsis, which is mediated in part by TLR2. However, GBS components that potently induce cytokines via TLR2 are largely unknown. We found that GBS strains of the same serotype differ in released factors that activate TLR2. Several lines of genetic and biochemical evidence indicated that lipoteichoic acid (LTA), the most widely s...
متن کاملGroup B Streptococcal Sepsis in a Newborn: a Case Report
Newborns’ bacterial infections due to group B Streptococcus (GBS) happen in two forms including early-onset disease or late-onset disease. In this paper, we report a case of early-onset GBS infection in a male infant. A 22-year-old primigravid woman delivers a term normal looking male infant. Nasal flaring, grunting, and poor feeding presented soon after birth. An empiric treatment wit...
متن کاملgroup b streptococcal sepsis in a newborn: a case report
newborns’ bacterial infections due to group b streptococcus (gbs) happen in two forms including early-onset disease or late-onset disease. in this paper, we report a case of early-onset gbs infection in a male infant. a 22-year-old primigravid woman delivers a term normal looking male infant. nasal flaring, grunting, and poor feeding presented soon after birth. an empiric treatment with intrave...
متن کامل[Inguinal cellulitis-adenitis in group B streptococcal late-onset sepsis].
Cellulitis-adenitis syndrome is a well-known presentation of Group B Streptococcus (GBS) late-onset sepsis in children. Although face and neck are most frequently involved, other locations can also be affected. Inguinal presentation is uncommon, but it may be the first clinical manifestation of a GBS bacteremia. We present two cases of cellulitis-adenitis syndrome with inguinal involvement in t...
متن کاملSevere fatal group B streptococcal sepsis in an adult.
Group B Streptococcal (GBS) sepsis is largely a disease of neonates and infantst, it is uncommon in adults, except in pregnancy and Purperium. Its rising incidence has been increasingly recognised among immunocompromised adult patients. It has also been sporadically reported among immunocompetent adults patients where it has a predorminantly similar presentation as in neonates i.e., as soft tis...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2008
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.180.9.6149